There are a lot of cool features with Apple iOS 6 that Scott announced in the WWDC keynote.
First in the list that I liked was the Do Not Disturb (DND)/Call Control, which tells your iPhone not to bother you with push notifications or SMSs. You could also choose not to receive calls at all. You could even specify the numbers from which you don’t want to hear.
The best part of this new feature is, it would let you reply automatically to the missed calls with text or just add those calls as a reminded to make a call back. You could also include Geo tagging, so that you can be hinted once you leave office/home.